HMAO-B-IN-8
HMAO-B-IN-8 (Compound 23) is a hMAO-B, eeAChE, COX-2 and 5-LOX inhibitor, with IC50 values of 0.037 μM, 0.071 μM, 14.3 μM and 0.59 μM, respectively. hMAO-B-IN-8 can be used for the research of Alzheimer's disease[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE) ; COX; Lipoxygenase; Monoamine Oxidase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hmao-b-in-8.html
Smiles
O=C(NC1=NC2=CC=C(O)C=C2S1)/C=C/C3=CC=C(C4=CC=CC=C4)C=C3
Molecular Formula
C22H16N2O2S
Molecular Weight
372.44
References & Citations
[1]Hussain F, et al. Exploitation of the multitarget role of new ferulic and gallic acid derivatives in oxidative stress-related Alzheimer's disease therapies: design, synthesis and bioevaluation. RSC Adv. 2024 Mar 28;14 (15) :10304-10321.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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