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Ziapin 2

Ziapin 2 is a molecular optomechanical light transducer. Ziapin 2 is an amphiphilic azobenzene with a strong non-covalent affinity to the plasma membrane. Ziapin 2 can be used to photo-modulate the membrane potential in cells of the Gram-positive bacterium Bacillus subtilis. Ziapin 2 enters the lipid membrane very rapidly (≈ 40 ns) [1][2].

Product Specifications

CAS Number

2399497-60-8

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ziapin-2.html

Purity

95.52

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

N(CCCCCC[N+]1=CC=CC=C1)(C2=CC=C(C=C2)/N=N/C3=CC=C(N4CCCCCC4)C=C3)CCCCCC[N+]5=CC=CC=C5.[Br-].[Br-]

Molecular Formula

C40H54Br2N6

Molecular Weight

778.70

References & Citations

[1]de Souza-Guerreiro TC, et al. Membrane Targeted Azobenzene Drives Optical Modulation of Bacterial Membrane Potential. Adv Sci (Weinh) . 2023 Mar;10 (8) :e2205007.|[2]Paternò GM, et al. The Effect of an Intramembrane Light-Actuator on the Dynamics of Phospholipids in Model Membranes and Intact Cells. Langmuir. 2020 Oct 6;36 (39) :11517-11527.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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