Ziapin 2
Ziapin 2 is a molecular optomechanical light transducer. Ziapin 2 is an amphiphilic azobenzene with a strong non-covalent affinity to the plasma membrane. Ziapin 2 can be used to photo-modulate the membrane potential in cells of the Gram-positive bacterium Bacillus subtilis. Ziapin 2 enters the lipid membrane very rapidly (≈ 40 ns) [1][2].
Product Specifications
CAS Number
2399497-60-8
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ziapin-2.html
Purity
95.52
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
N(CCCCCC[N+]1=CC=CC=C1)(C2=CC=C(C=C2)/N=N/C3=CC=C(N4CCCCCC4)C=C3)CCCCCC[N+]5=CC=CC=C5.[Br-].[Br-]
Molecular Formula
C40H54Br2N6
Molecular Weight
778.70
References & Citations
[1]de Souza-Guerreiro TC, et al. Membrane Targeted Azobenzene Drives Optical Modulation of Bacterial Membrane Potential. Adv Sci (Weinh) . 2023 Mar;10 (8) :e2205007.|[2]Paternò GM, et al. The Effect of an Intramembrane Light-Actuator on the Dynamics of Phospholipids in Model Membranes and Intact Cells. Langmuir. 2020 Oct 6;36 (39) :11517-11527.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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