ALRT1550
ALRT1550 (LGD1550) is a selective retinoic acid receptor (RAR) agonist that binds RARs with exceptional potency, with Kd values of approximately 1-4 nM. ALRT1550 exhibits anti-proliferative activity, with an IC50 value of 0.22 nM in UMSCC-22B squamous carcinoma cells. In a mouse tumor xenograft model, ALRT1550 inhibited tumor growth in a dose-dependent manner, achieving a maximum inhibition rate of 89%. ALRT1550 is applicable for research in the field of cancer[1][2].
Product Specifications
CAS Number
178600-20-9
Product Name Alternative
LGD1550
UNSPSC
12352005
Target
RAR/RXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alrt1550.html
Smiles
OC(/C=C(C)/C=C/C=C(C1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1)\C)=O
Molecular Formula
C23H32O2
Molecular Weight
340.50
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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