5 (6) -Carboxyfluorescein

5 (6) -Carboxyfluorescein (5 (6) -FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5 (6) -Carboxyfluorescein (5 (6) -FAM) can be used to label proteins, peptides and nucleotides. 5 (6) -Carboxyfluorescein can be used for the detection of tumour areas in vivo[1][2].

Product Specifications

CAS Number

[72088-94-9]

Product Name Alternative

5 (6) -FAM; 5- (and-6) -Carboxyfluorescein mixed isomers

UNSPSC

12171500

Hazard Statement

H319

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5_6_-Carboxyfluorescein.html

Purity

99.66

Solubility

DMSO : 58.33 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C2(O3)C(C=C(C(O)=O)C=C4)=C4C3=O)C(OC5=C2C=CC(O)=C5)=C1.OC6=CC=C(C7(O8)C(C=CC(C(O)=O)=C9)=C9C8=O)C(OC%10=C7C=CC(O)=C%10)=C6

Molecular Formula

C42H24O14

Molecular Weight

752.63

Precautions

H319

References & Citations

[1]Wen Ma, et al. A Cell Membrane-Targeting Self-Delivery Chimeric Peptide for Enhanced Photodynamic Therapy and In Situ Therapeutic Feedback. Adv Healthc Mater. 2020 Jan;9 (1) :e1901100.|[2]Maksim V Kvach, et al. 5 (6) -carboxyfluorescein revisited: new protecting group, separation of isomers, and their spectral properties on oligonucleotides. Bioconjug Chem. Sep-Oct 2007;18 (5) :1691-6.