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Boc-Val-Cit-OH

Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

[870487-08-4]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-val-cit-oh.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(O)[C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OC(C)(C)C)=O)=O

Molecular Formula

C16H30N4O6

Molecular Weight

374.43

Precautions

H302, H315, H319, H335

References & Citations

[1]Kevin HAMBLETT, et al. Anti-her2 biparatopic antibody-drug conjugates and methods of use. WO2019173911A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker; Protease Cleavable Linker

Available Sizes

Curated Selection

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