Anticancer agent 193
Product Specifications
UNSPSC Description
Anticancer agent 193 (compound D3-3) is an inducer of ferritinophagy, eventually triggering ferroptosis. Anticancer agent 193 induces the production of lipid ROS, and significantly promoted colorectal cancer cells to release the ferrous ion in an autophagy-dependent manner[1].
Target Antigen
Autophagy; Ferroptosis; Reactive Oxygen Species
Type
Reference compound
Related Pathways
Apoptosis;Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-193.html
Solubility
10 mM in DMSO
Smiles
O=C(CCCCCCCCCCCNC(C(Cl)=C)=O)OC1=C2C(C[C@H](N(C)CC3)[C@](C=C4OC)([H])[C@@]23CC4=O)=CC=C1OC
Molecular Weight
615.20
References & Citations
[1]Ling Zhu, et al. Identification of a ferritinophagy inducer via sinomenine modification for the treatment of colorectal cancer. Eur J Med Chem. 2024 Feb 21:268:116250.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162310/Anticancer-agent-193-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162310/
Clinical Information
No Development Reported
CAS Number
9007-83-4
Curated Selection
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