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Anticancer agent 193

Anticancer agent 193 (compound D3-3) is an inducer of ferritinophagy, eventually triggering ferroptosis. Anticancer agent 193 induces the production of lipid ROS, and significantly promoted colorectal cancer cells to release the ferrous ion in an autophagy-dependent manner[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Autophagy; Ferroptosis; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-193.html

Solubility

10 mM in DMSO

Smiles

O=C(CCCCCCCCCCCNC(C(Cl)=C)=O)OC1=C2C(C[C@H](N(C)CC3)[C@](C=C4OC)([H])[C@@]23CC4=O)=CC=C1OC

Molecular Formula

C34H47ClN2O6

Molecular Weight

615.20

References & Citations

[1]Ling Zhu, et al. Identification of a ferritinophagy inducer via sinomenine modification for the treatment of colorectal cancer. Eur J Med Chem. 2024 Feb 21:268:116250.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-162310/Anticancer-agent-193-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-162310/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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