10-Formyl-5,8-dideazafolic acid
10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor[1].
Product Specifications
CAS Number
[61038-31-1]
UNSPSC
12352005
Target
Thymidylate Synthase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/10-formyl-5-8-dideazafolic-acid.html
Purity
96.04
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C2=CC(CN(C3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O)C=O)=CC=C2NC(N)=N1
Molecular Formula
C22H21N5O7
Molecular Weight
467.43
References & Citations
[1]Reddy MR, et, al. Calculation of solvation and binding free energy differences for folate-based inhibitors of the enzyme thymidylate synthase. J. Am. Chem. Soc. 1992, 114, 26, 10117-10122.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K1351603 1.0 µg DNA
MSX1 sgRNA CRISPR Lentivector (Human) (Target 2)
Sign In for Pricing
View Details 2060885/A1 1 Each
BOTTLES, REAGENT, AMBER, NARROW NECK, WITH PP STOPPER
Sign In for Pricing
View Details 
126952-ML550 100 µL
FOXJ2 (Forkhead Box Protein J2, Fork Head Homologous X, FHX) (MaxLight 550)
Sign In for Pricing
View Details