10-Formyl-5,8-dideazafolic acid
10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor[1].
Product Specifications
CAS Number
[61038-31-1]
UNSPSC
12352005
Target
Thymidylate Synthase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/10-formyl-5-8-dideazafolic-acid.html
Purity
96.04
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C2=CC(CN(C3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O)C=O)=CC=C2NC(N)=N1
Molecular Formula
C22H21N5O7
Molecular Weight
467.43
References & Citations
[1]Reddy MR, et, al. Calculation of solvation and binding free energy differences for folate-based inhibitors of the enzyme thymidylate synthase. J. Am. Chem. Soc. 1992, 114, 26, 10117-10122.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K0121807 1.0 µg DNA
ARL6 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
Sign In for Pricing
View Details 
K0850107 1.0 µg DNA
GDF11 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
Sign In for Pricing
View Details 
MBS1489058-01 0.05 mg
Rabbit anti-human Macrophage metalloelastase polyclonal Antibody, FITC
Sign In for Pricing
View Details MBS1489058-02 0.1 mg
Rabbit anti-human Macrophage metalloelastase polyclonal Antibody, FITC
Sign In for Pricing
View Details MBS1489058-03 5x 0.1 mg
Rabbit anti-human Macrophage metalloelastase polyclonal Antibody, FITC
Sign In for Pricing
View Details