10-Formyl-5,8-dideazafolic acid
10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor[1].
Product Specifications
CAS Number
[61038-31-1]
UNSPSC
12352005
Target
Thymidylate Synthase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/10-formyl-5-8-dideazafolic-acid.html
Purity
96.04
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C2=CC(CN(C3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O)C=O)=CC=C2NC(N)=N1
Molecular Formula
C22H21N5O7
Molecular Weight
467.43
References & Citations
[1]Reddy MR, et, al. Calculation of solvation and binding free energy differences for folate-based inhibitors of the enzyme thymidylate synthase. J. Am. Chem. Soc. 1992, 114, 26, 10117-10122.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4995103 1.0 µg DNA
Prrc2b sgRNA CRISPR Lentivector (Mouse) (Target 2)
Sign In for Pricing
View Details 
MBS9942306 Inquire
Chicken Receptor Tyrosine-Protein Kinase erbB-2 (ERBB2) ELISA Kit
Sign In for Pricing
View Details 
039962-AP 200 µL
PHLDA2, CT (PHLDA2, BWR1C, HLDA2, IPL, TSSC3, Pleckstrin homology-like domain family A member 2, Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein, Imprinted in placenta and liver protein, Tumor-suppressing STF cDNA 3 protein, Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein, p17-Beckwith-Wiedemann region 1 C) (AP) discontinued
Sign In for Pricing
View Details