AD-5584
AD-5584 is an ACSS2 inhibitor with blood-brain permeability. AD-5584 can significantly reduce lipid storage, reduce colony formation, and increase cell death. AD-5584 has antitumor activity[1].
Product Specifications
CAS Number
2306525-79-9
UNSPSC
12352005
Target
Acetyl-CoA Carboxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ad-5584.html
Purity
99.86
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
FC1=CC=C(C(N2CCCCC2)C(N(C)CC3=NC4=CC(Cl)=CC=C4N3)=O)C=C1
Molecular Formula
C22H24ClFN4O
Molecular Weight
414.90
References & Citations
[1]Esquea E, et al. Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth. bioRxiv [Preprint]. 2023 Dec 23:2023.12.22.573073.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040972-100 1x 100 µL
Myeloid-Associated Differentiation Marker (MYADM/972), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
RG236474 10 µg
C2orf43 (LDAH) (NM_001282721) Human Tagged ORF Clone
Sign In for Pricing
View Details