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Gardneramine

Product Specifications

UNSPSC Description

Gardneramine is an orally active alkaloid that acts like papaverine. Gardneramine has peripheral vascular diastolic effect, direct inhibition on myocardium and central inhibition. Gardneramine showed antihypertensive, vasodilatation and atrial inhibition effects in rabbit, dog and guinea pig models, respectively. Gardneramine also inhibits the movement of smooth muscle organs such as the stomach and intestines[1].

Target Antigen

Others

Type

Natural Products

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/gardneramine.html

Solubility

10 mM in DMSO

Smiles

COC1=C2C34C5N(C/6)[C@@]([C@](COC4=NC2=C(OC)C=C1OC)([H])[C@@](C6=C\COC)([H])C5)([H])C3

Molecular Weight

412.48

References & Citations

[1]Harada M, et al. [Pharmacological studies on gardneria alkaloids. II. Peripheral effects (effects on circulatory and digestive systems)]. Yakugaku Zasshi. 1972 Dec;92(12):1540-6. Japanese.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N3931/Gardneramine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N3931/

Clinical Information

No Development Reported

CAS Number

34274-91-4

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