L-691678
L-691678 can bind to FLAP by recognizing the amino acid residues of 5-lipoxygenase-activating protein (FLAP), thereby inhibiting leukotriene biosynthesis. L-691678 can be used in the study of leukotriene-related diseases such as allergies, asthma, and inflammation[1].
Product Specifications
CAS Number
144210-49-1
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/l-691678.html
Smiles
O=C(C(C)(CC(N1CC2=CC=C(C=C2)I)=C(C3=C1C=CC(OCC4=NC5=CC=CC=C5C=C4)=C3)S(=O)(C6=CC=C(C=C6)N=[N+]=[N-])=O)C)O
Molecular Formula
C36H30IN5O5S
Molecular Weight
771.62
References & Citations
[1]Mancini J A, et al. 5-Lipoxygenase-activating protein is the target of a novel hybrid of two classes of leukotriene biosynthesis inhibitors[J]. Molecular pharmacology, 1992, 41 (2) : 267-272.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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