SC-67655
SC 67655 is a potent and stable pentapeptide MHC class II haplotype DR4 (DR4 Dw4 or DRB 1"0401) ligand with an IC50 of 50 nM. SC 67655 can be used for the study of autoimmune diseases[1].
Product Specifications
CAS Number
182134-00-5
UNSPSC
12352209
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sc-67655.html
Smiles
C[C@@H](CC(N[C@@H](C(C)C)C(N1[C@H](C(N[C@@H](CC(O)=O)C(N2CCC[C@H]2C(N[C@H](C(NCCC)=O)[C@H](O)C)=O)=O)=O)CCCC1)=O)=O)C3CCCCC3
Molecular Formula
C37H62N6O9
Molecular Weight
734.92
References & Citations
[1]S L Woulfe, et al. A peptidomimetic that specifically inhibits human leukocyte antigen DRB1*0401-restricted T cell proliferation. J Pharmacol Exp Ther. 1997 May;281 (2) :663-9.|[2]Gunnar J. Hanson, et al. (1996) . Design of MHC class II (DR4) ligands using conformationally restricted imino acids at p3 and p5. , 6 (16), 1931-1936.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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