Dihydronarwedine

Dihydronarwedine (Lycoraminone) is the alkaloid. Dihydronarwedine inhibits 39% activity of glycogen synthase kinase-3β (GSK-3β) at a concentration of 10 μM[1].

Product Specifications

CAS Number

[21041-10-1]

Product Name Alternative

Lycoraminone

UNSPSC

12352005

Hazard Statement

H300+H310

Target

GSK-3

Type

Natural Products

Related Pathways

PI3K/Akt/mTOR; Stem Cell/Wnt

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dihydronarwedine.html

Smiles

O=C1CC[C@@]23CCN(C)CC4=CC=C(OC)C(O[C@@]3([H])C1)=C24

Molecular Formula

C17H21NO3

Molecular Weight

287.35

Precautions

P262-P264-P270-P280-P302+P352-P330-P361+P364-P405-P501

References & Citations

[1]Hulcová D, et al., Amaryllidaceae alkaloids from Narcissus pseudonarcissus L. cv. Dutch Master as potential drugs in treatment of Alzheimer's disease. Phytochemistry. 2019 Sep;165:112055.