SHP2-IN-27
SHP2-IN-27 (compound 28) is an allosteric inhibitor of tyrosine phosphatase SH2[1].
Product Specifications
CAS Number
2376012-00-7
UNSPSC
12352005
Target
SHP2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/shp2-in-27.html
Solubility
10 mM in DMSO
Smiles
N[C@H](C[C@@H]1CC2)C[C@@H]2N1C3=CN=C4C(NC=C4C5=C(Cl)C6=CN(C)N=C6C=C5)=N3
Molecular Formula
C21H22ClN7
Molecular Weight
407.90
References & Citations
[1]Day JEH, et al. Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2) . J Med Chem. 2024 Mar 10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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