Fipexide (hydrochloride)

Fipexide hydrochloride, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide hydrochloride reduces striatal adenylate cyclase activity. Fipexide hydrochloride has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide hydrochloride is used for senile dementia research. Fipexide hydrochloride acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection[1][2].

Product Specifications

CAS Number

[34161-23-4]

UNSPSC

12352005

Target

Adenylate Cyclase; Dopamine Transporter

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fipexide-hydrochloride.html

Concentration

10mM

Purity

99.88

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

ClC1=CC=C(OCC(N2CCN(CC3=CC=C(OCO4)C4=C3)CC2)=O)C=C1.[H]Cl

Molecular Formula

C20H22Cl2N2O4

Molecular Weight

425.31

References & Citations

[1]A Marino, et al. Fipexide improvement of cognitive functions in rat: behavioural and neurochemical studies. Pharmacol Res. Mar-Apr 1990;22 (2) :179-87.|[2]Takeshi Nakano, et al.FPX is a Novel Chemical Inducer that Promotes Callus Formation and Shoot Regeneration in Plants. Plant Cell Physiol. 2018 Aug 1;59 (8) :1555-1567.|[3]M G Genkova-Papazova, et al. Piracetam and fipexide prevent PTZ-kindling-provoked amnesia in rats. Eur Neuropsychopharmacol. 1996 Nov;6 (4) :285-90.