DYR684e
Product Specifications
CAS Number
2377851-46-0
UNSPSC Description
DYR684e is a ligand for E3 ligase, which can be used for synthesis of PROTAC degrader DYR684 (HY-168194)[1].
Target Antigen
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dyr684e.html
Smiles
O=C(C(N(C(C1=C2C=CC=C1NCC3=CN(C4CCNCC4)N=C3)=O)C2=O)CC5)NC5=O.Cl
Molecular Weight
472.92
References & Citations
[1]Wilms G, et al., Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B. J Med Chem. 2024 Oct 10;67(19):17259-17289.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Frequently Asked Questions
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