Glial Cell Line-derived Neurotrophic Factor

<strong>Human Glial Cell Line-derived Neurotrophic Factor</strong>_x000D_ <strong>Catalog number:</strong> B2010363_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Human Glial Cell Line-derived Neurotrophic Factor expressed in E. coli. This protein acts as a small protein that potently promotes the survival of many types of neurons._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuGDNF; ATF_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chang HM, Wu HC, Sun ZG, Lian F, Leung PCK. Neurotrophins and glial cell_x000D_ line-derived neurotrophic factor in the ovary: physiological and_x000D_ pathophysiological implications. Hum Reprod Update. 2019 Mar 1;25(2):224-242._x000D_ _x000D_ 2: Ayanlaja AA, Zhang B, Ji G, Gao Y, Wang J, Kanwore K, Gao D. The reversible_x000D_ effects of glial cell line-derived neurotrophic factor (GDNF) in the human_x000D_ brain. Semin Cancer Biol. 2018 Dec;53:212-222._x000D_ _x000D_ 3: Whone A, Luz M, Boca M, Woolley M, Mooney L, Dharia S, Broadfoot J, Cronin D,_x000D_ Schroers C, Barua NU, Longpre L, Barclay CL, Boiko C, Johnson GA, Fibiger HC,_x000D_ Harrison R, Lewis O, Pritchard G, Howell M, Irving C, Johnson D, Kinch S,_x000D_ Marshall C, Lawrence AD, Blinder S, Sossi V, Stoessl AJ, Skinner P, Mohr E, Gill_x000D_ SS. Randomized trial of intermittent intraputamenal glial cell line-derived_x000D_ neurotrophic factor in Parkinson's disease. Brain. 2019 Mar 1;142(3):512-525._x000D_ _x000D_ 4: Zhu S, Li Y, Bennett S, Chen J, Weng IZ, Huang L, Xu H, Xu J. The role of_x000D_ glial cell line-derived neurotrophic factor family member artemin in_x000D_ neurological disorders and cancers. Cell Prolif. 2020 Jul;53(7):e12860._x000D_ _x000D_ 5: Yamada J, Akeda K, Sano T, Iwasaki T, Takegami N, Sudo A. Expression of Glial_x000D_ Cell Line-derived Neurotrophic Factor in the Human Intervertebral Disc. Spine_x000D_ (Phila Pa 1976). 2020 Jul 1;45(13):E768-E775._x000D_ _x000D_ 6: Rosich K, Hanna BF, Ibrahim RK, Hellenbrand DJ, Hanna A. The Effects of Glial_x000D_ Cell Line-Derived Neurotrophic Factor after Spinal Cord Injury. J Neurotrauma._x000D_ 2017 Dec 15;34(24):3311-3325._x000D_ _x000D_ 7: Tsybko AS, Ilchibaeva TV, Popova NK. Role of glial cell line-derived_x000D_ neurotrophic factor in the pathogenesis and treatment of mood disorders. Rev_x000D_ Neurosci. 2017 Apr 1;28(3):219-233._x000D_ _x000D_ 8: Sidorova YA, Saarma M. Small Molecules and Peptides Targeting Glial Cell_x000D_ Line-Derived Neurotrophic Factor Receptors for the Treatment of_x000D_ Neurodegeneration. Int J Mol Sci. 2020 Sep 8;21(18):6575._x000D_ _x000D_ 9: Chen M, Ba H, Lu C, Dai J, Sun J. Glial Cell Line-Derived Neurotrophic Factor_x000D_ (GDNF) Promotes Angiogenesis through the Demethylation of the Fibromodulin_x000D_ (FMOD) Promoter in Glioblastoma. Med Sci Monit. 2018 Sep 3;24:6137-6143._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/28918204/">10: Duan X, Zhu T, Chen C, Zhang G, Zhang J, Wang L, Zhang L, Wang M, Wang X._x000D_ Serum glial cell line-derived neurotrophic factor levels and postoperative_x000D_ cognitive dysfunction after surgery for rheumatic heart disease. J Thorac_x000D_ Cardiovasc Surg. 2018 Mar;155(3):958-965.e1. </a>_x000D_ _x000D_ <strong>Products Related to Human Glial Cell Line-derived Neurotrophic Factor </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>