Suritozole
Suritozole (MGL-26479) is a cognitive enhancer that acts as a partial inverse agonist of benzodiazepine receptor sites on GABAA ion channel complexes. Suritozole can be used in the study of neurodegenerative diseases[1].
Product Specifications
CAS Number
110623-33-1
Product Name Alternative
MDL-26479
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/suritozole.html
Solubility
10 mM in DMSO
Smiles
S=C1N(N=C(N1C)C2=CC=CC(F)=C2)C
Molecular Formula
C10H10FN3S
Molecular Weight
223.27
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]O'Dell DM, et al. Chronic postinjury administration of MDL 26,479 (Suritozole), a negative modulator at the GABAA receptor, and cognitive impairment in rats following traumatic brain injury. J Neurosurg. 1995 Nov;83 (5) :878-83.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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