IL-11R alpha, Canine (HEK293)
IL-11R alpha (IL-11RA) is the IL-11 receptor subunit α and also acts as an agonist of IL-11. IL-11R alpha binds to IL6ST/gp130 on cell surfaces and induces signal transduction[1]. IL-11R alpha activates Jak family of tyrosine kinases, JAK1, JAK2, and TYK2[3]. IL-11R alpha induces proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells[4]. IL-11R alpha plays an important role in the progression and the differentiation of human gastric carcinomas[5]. IL-11R alpha Protein, Canine (HEK293) is a recombinant protein produced by HEK293 cells.
Product Specifications
Product Name Alternative
IL-11R alpha Protein, Canine (HEK293), Canine, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/il-11r-alpha-protein-canine-hek293.html
Molecular Formula
481588 (Gene_ID) A0A8I3S524/XP_538710 (V23-L363) (Accession)
Molecular Weight
Approximately 43-47 kDa, based on SDS-PAGE under reducing conditions.
References & Citations
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Scientific Category
Recombinant Proteins
Frequently Asked Questions
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