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DL-4-Hydroxy-2-ketoglutarate

DL-4-Hydroxy-2-ketoglutarate serves as a substrate for the enzymes GOT (glutamic oxalacetic aminotransferase) and 2-keto-4-hydroxyglutarate aldolase, facilitating the reversible breakdown of 2-keto-4-hydroxyglutarate into pyruvate and glyoxylate; it has also found applications in mass spectrometry for the swift analysis of negatively charged, water-soluble cellular metabolites.

Product Specifications

CAS Number

1187-99-1

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dl-4-hydroxy-2-ketoglutarate.html

Smiles

O=C(C(CC(C(O)=O)O)=O)O

Molecular Formula

C5H6O6

Molecular Weight

162.10

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Enzymic synthesis of 4-methyl- and 4-ethyl-L-glutamic acids |[2]2-Keto-4-hydroxyglutarate aldolase: purification and characterization of the homogeneous enzyme from bovine kidney|[3]Shotgun metabolomics approach for the analysis of negatively charged water-soluble cellular metabolites from mouse heart tissue

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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