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MSP-3

MSP-3 is a potent TRPV1 agonist, with an EC50 of 0.87 μM. MSP-3 exhibits neuroprotective and antinociceptive effects[1].

Product Specifications

CAS Number

1820968-63-5

UNSPSC

12352005

Hazard Statement

H315, H319, H401

Target

TRP Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/msp-3.html

Purity

98.53

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CCCC1=CC=CS1)NCC2=CC=C(C(OC)=C2)O

Molecular Formula

C16H19NO3S

Molecular Weight

305.39

Precautions

H315, H319, H401

References & Citations

[1]Aiello F, et, al. Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N- (4-Hydroxy-3-methoxybenzyl) -4- (thiophen-2-yl) butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress. ACS Chem Neurosci. 2016 Jun 15;7 (6) :737-48.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

TRPV1

Available Sizes

Frequently Asked Questions

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