APC Anti-Mouse CD122 Antibody[TM-Beta 1]
Product Specifications
Background
CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The TM-β1 antibody does inhibit IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
Abbreviation
CD122
Gene ID
16185
UniProt
P16297
Host
Rat
Reactivity
Mouse
Target
IL-2 Receptor β chain; IL-2Rβ
Clonality
Monoclonal
Clone
TM-Beta 1
Conjugation
APC
Applications
FCM
Concentration
0.2 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Product Datasheet
https://789.bio/ea/pp4gv5
Product MSDS
https://789.bio/eb/D4dSGC
Recommended Usage
6
Isotype
Rat IgG2b, κ
Available Sizes
Curated Selection
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