2'-Azido-2'-deoxyuridine
Product Specifications
UNSPSC Description
2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity[1]. 2'-Azido-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-azido-2-deoxyuridine.html
Smiles
O=C(C=C1)NC(N1[C@@H]([C@H](N=[N+]=[N-])[C@@H]2O)O[C@@H]2CO)=O
Molecular Weight
269.21
References & Citations
[1]Kang SH, et al. Biological activity and phosphorylation of 2<sub>'</sub>-azido-2<sub>'</sub>-deoxyuridine and 2<sub>'</sub>-azido-2<sub>'</sub>-deoxycytidine. Nucleosides Nucleotides. 1998 Jun;17(6):1077-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-135957/2-Azido-2-deoxyuridine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-135957/
CAS Number
26929-65-7
Available Sizes
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