2'-Azido-2'-deoxyuridine
2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity[1]. 2'-Azido-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[26929-65-7]
Product Name Alternative
N3dUrd
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-azido-2-deoxyuridine.html
Solubility
10 mM in DMSO
Smiles
O=C(C=C1)NC(N1[C@@H]([C@H](N=[N+]=[N-])[C@@H]2O)O[C@@H]2CO)=O
Molecular Formula
C9H11N5O5
Molecular Weight
269.21
References & Citations
''''
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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TRIAD3, CT (E3 Ubiquitin-protein Ligase RNF216, RING Finger Protein 216, Ubiquitin Conjugating Enzyme 7 Interacting Protein 1, Triad3 Protein, Zinc Finger Protein Inhibiting NF-kappa-B, Triad Domain-containing Protein 3, UBCE7IP1, RNF216, ZIN) (APC)
TRIAD3, CT (E3 Ubiquitin-protein Ligase RNF216, RING Finger Protein 216, Ubiquitin Conjugating Enzyme 7 Interacting Protein 1, Triad3 Protein, Zinc Finger Protein Inhibiting NF-kappa-B, Triad Domain-containing Protein 3, UBCE7IP1, RNF216, ZIN) (APC)
