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GPx-4 Rabbit Polyclonal Antibody

The GPx-4 Antibody is suitable for IF, IHC, WB. It is a Polyclonal, Unconjugated antibody which raised against Recombinant fusion protein of human GPx-4 .Purification: The antibody was purified by immunogen affinity chromatography.

Product Specifications

Product Name Alternative

Phospholipid hydroperoxide glutathione peroxidase mitochondrial; PHGPx; Glutathione peroxidase 4; GPx-4; GSHPx-4

UniProt

P36969

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human GPx-4

Target

GPX4

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Developmental Biology, Epigenetics

Purification

The antibody was purified by immunogen affinity chromatography.

Dilution

WB: 1:500-1:2000, IHC-P: 1:50-1:200, IF/ICC: 1:10-1:100

Form

Liquid

References & Citations

G Tian, J Li, W Wang, L Zhou FGF12 restrains mitochondria‐dependent ferroptosis in doxorubicin‐induced cardiomyocytes through the activation of FGFR1/AMPK/NRF2 signaling Drug Development Research, (2024), Xiaoshan Chen 1, Wei Wang 2, Wei Wei TRIM22 mechanism promoting KAT2A ubiquitination degradation to regulate ferroptosis in hepatocellular carcinoma cell invasion and metastasis Histol Histopathol ., (2024), F Ye, Y Xu, X Zhu, Q Ding, Y Wang, S Lu, Y Chen The mechanism of E3 ubiquitin ligase HERC1 regulating ferroptosis in lung adenocarcinoma cells Cancer Genetics, (2025), Yulin Li et al. Mechanism of the enterobacterial metabolite sodium butyrate mediating ferroptosis to affect osteogenic ability of BMSCs in mice with estrogen deficiency-caused osteoporosis via the PTEN/PI3K/AKT pathway Apoptosis, (2025), Li, Meng et al. Melatonin Inhibits the Ferroptosis Pathway in Rat Bone Marrow Mesenchymal Stem Cells by Activating the PI3K/AKT/mTOR Signaling Axis to Attenuate Steroid-Induced Osteoporosis Oxid Med Cell Longev, 2022, 8223737 (2022), Ma, Xiaojun et al. Lidocaine attenuates hypoxia/reoxygenation?induced inflammation, apoptosis and ferroptosis in lung epithelial cells by regulating the p38 MAPK pathway Mol Med Rep, 25, 150 (2022)

Pubmed id

39698827, 41205030, 36035224, 35244190

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

IF, IHC, WB

Host or Source

Rabbit

Preservative

0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Entrez

2879

Available Sizes

Frequently Asked Questions

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