Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Minodronic acid

Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain[1][2].

Product Specifications

CAS Number

180064-38-4

Product Name Alternative

YM-529

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; P2X Receptor

Type

Reference compound

Related Pathways

Apoptosis; Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/minodronic-acid.html

Purity

99.67

Solubility

H2O : 5 mg/mL (ultrasonic; warming; adjust pH to 10 with NaOH; heat to 80°C)

Smiles

OC(P(O)(O)=O)(P(O)(O)=O)CC1=CN=C2C=CC=CN21

Molecular Formula

C9H12N2O7P2

Molecular Weight

322.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Sato K, et al. A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo. Br J Cancer. 2006 Nov 20;95 (10) :1354-61.|[2]Tanaka M, et al. Minodronic acid induces morphological changes in osteoclasts at bone resorption sites and reaches a level required for antagonism of purinergic P2X2/3 receptors. J Bone Miner Metab. 2018 Jan;36 (1) :54-63.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

P2X2 Receptor; P2X3 Receptor

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

IgA Secretory Component (SC05), CF568 conjugate, 0.1mg/mL
BNC680050-100 1x 100 µL

IgA Secretory Component (SC05), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD71 (66IG10), CF405S conjugate, 0.1mg/mL
BNC040871-500 1x 500 µL

CD71 (66IG10), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Cytokeratin, LMW (AE-1), CF568 conjugate, 0.1mg/mL
BNC680253-100 1x 100 µL

Cytokeratin, LMW (AE-1), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
MCM7 (Proliferation Marker) (MCM7/1468), CF405S conjugate, 0.1mg/mL
BNC041468-100 1x 100 µL

MCM7 (Proliferation Marker) (MCM7/1468), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
EGFR (GFR1195), CF568 conjugate, 0.1mg/mL
BNC681195-100 1x 100 µL

EGFR (GFR1195), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Bcl-6 (Follicular Lymphoma Marker) (rBCL6/1718), CF594 conjugate, 0.1mg/mL
BNC942498-100 1x 100 µL

Bcl-6 (Follicular Lymphoma Marker) (rBCL6/1718), CF594 conjugate, 0.1mg/mL

Sign In for Pricing
View Details