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13,14-Dihydro-15-keto prostaglandin D2-d9

Selected Variant

HY-118830S1

Size: 1 Each

13,14-Dihydro-15-keto prostaglandin D2-d9 (DK-PGD2-d9) is deuterium labeled 13,14-Dihydro-15-keto prostaglandin D2. 13, 14-Dihydro-15-keto prostaglandin D2 (DK-PGD2) is a PGD2 metabolite formed by the 15-hydroxyl PGDH pathway. 13, 14-Dihydro-15-keto prostaglandin D2 is a selective agonist for the DP2 receptor. 13, 14-Dihydro-15-keto prostaglandin D2 can inhibit ion flux in canine colonic mucosa preparation[1][2].

Product Specifications

CAS Number

2738376-77-5

Product Name Alternative

DK-PGD2-d9; 15-Oxo-13,14-dihydro-PGD2-d9; 13,14-Dihydro-15-keto-PGD2-d9

UNSPSC

12352211

Target

Isotope-Labeled Compounds; Prostaglandin Receptor

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Others

Field of Research

Endocrinology

Smiles

O[C@H]([C@@H]([C@H]1CCC(CC([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])=O)C/C=C\CCCC(O)=O)CC1=O

Molecular Formula

C20H23D9O5

Molecular Weight

361.52

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Larsen P, et al. Calcium-stimulated short-circuit currents in the canine proximal colonic epithelium: effects of DK-PGD2, a metabolite of prostaglandin D2. Can J Physiol Pharmacol. 2002 Nov;80 (11) :1085-94.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Price

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