Mechercharmycin A
Mechercharmycin A is a cytotoxic substance isolated from marine-derived Thermoactinomyces sp. YM3-251. Mechercharmycin A exhibits relatively strong antitumor activity[1][2].
Product Specifications
CAS Number
822520-96-7
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mechercharmycin-a.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@](C(N[C@H](C(NC(C1=NC2=CO1)=C)=O)C(C)C)=O)([H])[C@@H](C)CC)C3=C(C4=CC=CC=C4)OC(C5=COC(C6=CSC(C7=COC2=N7)=N6)=N5)=N3
Molecular Formula
C35H32N8O7S
Molecular Weight
708.74
References & Citations
[1]Kanoh K, et, al. Mechercharmycins A and B, cytotoxic substances from marine-derived Thermoactinomyces sp. YM3-251. J Antibiot (Tokyo) . 2005 Apr;58 (4) :289-92.|[2]Hernández D, et, al. Synthesis and antitumor activity of mechercharmycin A analogues. J Med Chem. 2008 Sep 25;51 (18) :5722-30.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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