ICL-CCIC-0019
ICL-CCIC-0019 is an inhibitor of choline kinase α (CHKα) . ICL-CCIC-0019 induces G1 block, endoplasmic reticulum stress apoptosis in cancer cell lines[1].
Product Specifications
CAS Number
[936498-64-5]
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/icl-ccic-0019.html
Purity
97.80
Solubility
DMSO : 8.33 mg/mL (ultrasonic)
Smiles
CN(C)C1=CC=[N+](C=C1)CCCCCCCCCCCC[N+]2=CC=C(C=C2)N(C)C.[Br-].[Br-]
Molecular Formula
C26H44Br2N4
Molecular Weight
572.46
References & Citations
[1]Trousil S, et al. The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth. Oncotarget. 2016 Jun 14;7 (24) :37103-37120.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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