IA9
IA9 (human TREM-2 182-190) is a potent, CNS-penetrant TREM-2 inhibitor. IA9 can diminish the release of proinflammatory cytokines and suppress joint inflammation and damage in a Collagen -induced arthritis (CIA) mouse model. IA9 can be used for neuroinflammation PET imaging. IA9 can be used for Rheumatoid arthritis (RA) and neuroinflammation research[1][2].
Product Specifications
Product Name Alternative
Human TREM-2 182-190
UNSPSC
12352209
Target
TREM receptor
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ia9.html
Purity
98.36
Solubility
DMSO : 22.22 mg/mL (ultrasonic;adjust pH to 4 with 1 M HCL)
Smiles
Molecular Formula
C51H88N10O10
Molecular Weight
1001.31
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
TREM-2
Available Sizes
Frequently Asked Questions
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