Anti-inflammatory agent 51

Anti-inflammatory agent 51 (compound 11d) is an amide/sulfonamide derivative with anti-inflammatory activities. Anti-inflammatory agent 51 inhibits NF-κB activation, has the potential for acute lung injury and ulcerative colitis research[1].

Product Specifications

CAS Number

[2911610-03-0]

UNSPSC

12352005

Target

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-51.html

Purity

98.08

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=S(NCC1=CC=CC=N1)(C2=CC=C(C([N+]([O-])=O)=C2)N3CCN(CC3)C4=CC=C(C=C4)[N+]([O-])=O)=O

Molecular Formula

C22H22N6O6S

Molecular Weight

498.51

References & Citations

[1]Pan Chen, et al. Design, synthesis, and bioactivity evaluation of novel amide/sulfonamide derivatives as potential anti-inflammatory agents against acute lung injury and ulcerative colitis. Eur J Med Chem. 2023 Aug 2;259:115706.