Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Empagliflozin-d4

Selected Variant

HY-15409S-01

Size: 1 mg

Empagliflozin-d4 is deuterium labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2[1].

Product Specifications

CAS Number

2749293-95-4

Product Name Alternative

BI 10773-d4

UNSPSC

12352005

Target

SGLT

Type

Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Purity

98.40

Solubility

10 mM in DMSO|DMSO : 50mg/mL (ultrasonic)

Smiles

ClC(C=CC([C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)=C2)=C2CC3=C(C([2H])=C(C([2H])=C3[2H])O[C@H]4CCOC4)[2H]

Molecular Formula

C23H23D4ClO7

Molecular Weight

454.93

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Cheng ST, et al. The Effects of Empagliflozin, an SGLT2 Inhibitor, on Pancreatic β-Cell Mass and Glucose Homeostasis in Type 1 Diabetes. PLoS One. 2016 Jan 25;11 (1) :e0147391.|[3]Grempler R, et al. Empagliflozin, a novel selective sodium glucose cotransporter-2 (SGLT-2) inhibitor: characterisation and comparison with other SGLT-2 inhibitors. Diabetes Obes Metab. 2012 Jan;14 (1) :83-90.|[4]Nikole J.ByrneBSc, et al. Empagliflozin Prevents Worsening of Cardiac Function in an Experimental Model of Pressure Overload-Induced Heart Failure. JACC Basic Transl Sci. 2017 Aug;2 (4) :347-354.|[5]Sakaeda T, et al. Susceptibility to serious skin and subcutaneous tissue disorders and skin tissue distribution of sodium-dependent glucose co-transporter type 2 (SGLT2) inhibitors. Int J Med Sci. 2018 Jun 13;15 (9) :937-943.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Isoform

SGLT2

Available Sizes

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Involucrin (IVRN/827), CF647 conjugate, 0.1mg/mL
BNC470827-100 1x 100 µL

Involucrin (IVRN/827), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Human Serpin G1 ELISA Kit PicoKine®
EK1667 96 Well With Removable Strips

Human Serpin G1 ELISA Kit PicoKine®

Sign In for Pricing
View Details
Anti-Ku80/XRCC5 Antibody Picoband® (APC Conjugate)
PB9464-APC 100 µg/Vial

Anti-Ku80/XRCC5 Antibody Picoband® (APC Conjugate)

Sign In for Pricing
View Details