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Pomalidomide-5'-PEG8-C2-COOH

Product Specifications

UNSPSC Description

Pomalidomide-5'-PEG8-C2-COOH is an E3 Ligase Ligand-Linker Conjugates, consisting of Pomalidomide (HY-10984) and a linker. Pomalidomide-5'-PEG8-C2-COOH can be used for synthesis of PROTACs[1].

Target Antigen

E3 Ligase Ligand-Linker Conjugates

Type

ADC Related

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pomalidomide-5-peg8-c2-cooh.html

Purity

98.21

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Molecular Weight

697.73

References & Citations

[1]Posternak G, et al. Functional characterization of a PROTAC directed against BRAF mutant V600E. Nat Chem Biol. 2020 Nov;16(11):1170-1178.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W580022/Pomalidomide-5-PEG8-C2-COOH-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W580022/Pomalidomide-5-PEG8-C2-COOH-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2138440-78-3

Available Sizes

Curated Selection

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