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GSK299423

GSK 299423 is an antibiotic agent.GSK299423 shows potent inhibition of supercoiling by DNA gyrase from S. aureus (IC50=14 nM) and Escherichia coli (IC50=100 nM[1].

Product Specifications

CAS Number

1352149-24-6

UNSPSC

12352005

Target

Bacterial; DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/gsk299423.html

Smiles

N#CC1=CN=C2C=CC(OC)=CC2=C1CCN3CCC(CC3)NCC4=NC=C5OCSC5=C4

Molecular Formula

C25H27N5O2S

Molecular Weight

461.58

References & Citations

[1]Bax BD, et al. Type IIA topoisomerase inhibition by a new class of antibacterial agents. Nature. 2010;466 (7309) :935-940.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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