GSK299423
GSK 299423 is an antibiotic agent.GSK299423 shows potent inhibition of supercoiling by DNA gyrase from S. aureus (IC50=14 nM) and Escherichia coli (IC50=100 nM[1].
Product Specifications
CAS Number
1352149-24-6
UNSPSC
12352005
Target
Bacterial; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gsk299423.html
Smiles
N#CC1=CN=C2C=CC(OC)=CC2=C1CCN3CCC(CC3)NCC4=NC=C5OCSC5=C4
Molecular Formula
C25H27N5O2S
Molecular Weight
461.58
References & Citations
[1]Bax BD, et al. Type IIA topoisomerase inhibition by a new class of antibacterial agents. Nature. 2010;466 (7309) :935-940.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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