MoTPS1-IN-1

MoTPS1-IN-1 (Compound j11), an antifungal agent, is a MoTPS1 inhibitor. MoTPS1-IN-1 acts by interation with Glu396 in MoTPS1. MoTPS1-IN-1 inhibits pathogenicity of M. oryzae[1].

Product Specifications

CAS Number

[2991072-02-5]

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/motps1-in-1.html

Purity

99.50

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(COC1=CC=C2OCOC2=C1)CNC3CCN(CC3)CC4=CC=C(C=C4)C(F)(F)F

Molecular Formula

C23H27F3N2O4

Molecular Weight

452.47

References & Citations

[1]Jiang Z, et al. Discovery of novel isopropanolamine inhibitors against MoTPS1 as potential fungicides with unique mechanisms. Eur J Med Chem. 2023 Nov 15;260:115755.