AZD 6482
AZD 6482 (KIN-193) is a potent and selective p110β inhibitor with an IC50 of 0.69 nM.
Product Specifications
CAS Number
[1173900-33-8]
Product Name Alternative
KIN-193
UNSPSC
12352005
Hazard Statement
H302, H315, H320, H335
Target
Autophagy; PI3K
Type
Reference compound
Related Pathways
Autophagy; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/AZD-6482.html
Concentration
10mM
Purity
99.93
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1N2C(C([C@H](NC3=CC=CC=C3C(O)=O)C)=CC(C)=C2)=NC(N4CCOCC4)=C1
Molecular Formula
C22H24N4O4
Molecular Weight
408.45
Precautions
H302, H315, H320, H335
References & Citations
[1]Ni J, et al. Functional characterization of an isoform-selective inhibitor of PI3K-p110β as a potential anticancer agent. Cancer Discov. 2012 May;2 (5) :425-33.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
PI3KC2β; PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ; Vps34
Available Sizes
Curated Selection
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