KRN2 (bromide)
KRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM.
Product Specifications
CAS Number
1390654-28-0
UNSPSC
12352005
Target
Nuclear Factor of activated T Cells (NFAT)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/KRN2_bromide.html
Purity
98.81
Solubility
DMSO : 18.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
COC1=C(OC)C2=C[N+]3=C(C(C(CC3)=C4)=CC5=C4OCO5)C(CC6=CC=CC=C6F)=C2C=C1.[Br-]
Molecular Formula
C27H23BrFNO4
Molecular Weight
524.38
References & Citations
[1]Han EJ, et al. Suppression of NFAT5-mediated Inflammation and Chronic Arthritis by Novel κB-binding Inhibitors. EBioMedicine. 2017 Apr;18:261-273.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Citation 01
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Anti-Chikungunya E1 Protein-Purified?in vivo?GOLD? Functional Grade
C1orf137 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)