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Boc-NH-PEG2-C2-NHS ester

Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2183440-73-3]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-nh-peg2-c2-nhs-ester.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

CC(C)(C)OC(NCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O

Molecular Formula

C16H26N2O8

Molecular Weight

374.39

Precautions

H315, H319

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers

Available Sizes

Curated Selection

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