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Phospho-STAT1 (Y701) Recombinant Rabbit Monoclonal Antibody [PSH04-02]

Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. It is a member of the STAT protein family. All STAT molecules are phosphorylated by receptor associated kinases, that causes activation, dimerization by forming homo- or heterodimers and finally translocate to nucleus to work as transcription factors. Specifically STAT1 can be activated by several ligands such as Interferon alpha (IFNα), Interferon gamma (IFNγ), Epidermal Growth Factor (EGF), Platelet Derived Growth Factor (PDGF), Interleukin 6 (IL-6), or IL-27.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Signal transducer and activator of transcription 1 91kD antibody CANDF7 antibody DKFZp686B04100 antibody IMD31A antibody IMD31B antibody IMD31C antibody ISGF 3 antibody ISGF-3 antibody OTTHUMP00000163552 antibody OTTHUMP00000165046 antibody OTTHUMP00000165047 antibody OTTHUMP00000205845 antibody Signal transducer and activator of transcription 1 91kDa antibody Signal transducer and activator of transcription 1 antibody Signal transducer and activator of transcription 1, 91kD antibody Signal transducer and activator of transcription 1-alpha/beta antibody STAT 1 antibody Stat1 antibody STAT1_HUMAN antibody STAT91 antibody Transcription factor ISGF 3 components p91 p84 antibody Transcription factor ISGF-3 components p91/p84 antibody Transcription factor ISGF3 components p91/p84 antibody XStat1 antibody

Abbreviation

STAT1

Swiss Prot

P42224 Human

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic phospho-peptide corresponding to residues surrounding Tyr701 of Human STAT1.

Isotype

IgG

Clone

PSH04-02

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell

Positive Control

HeLa treated with 100ng/mL IFNγ for 30 minutes cell lysate, HeLa treated with 50ng/mL IFNα1 for 30 minutes cell lysate, A431 treated with 100ng/mL EGF for 30 minutes cell lysate, HeLa cells treated with 100ng/mL IFNα1 for 5 minutes.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 87 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

Frequently Asked Questions

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