OH-C-Chol

OH-C-Chol is a cationic liposome that serves as a siRNA delivery vehicle. OH-C-Chol (LP-C) and OH-NC-Chol (LP-NC) /siRNA complexes (lipoplexes) showed better performance than NP-C and NP-NC/siRNA complexes (nanocomplexes), respectively.) greater gene silencing effect[1].

Product Specifications

CAS Number

[496801-51-5]

UNSPSC

12352200

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/oh-c-chol.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(NCCNCCO)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C

Molecular Formula

C32H56N2O3

Molecular Weight

516.80

References & Citations

[1]Hattori Y, et al. siRNA delivery into tumor cells by cationic cholesterol derivative-based nanoparticles and liposomes. Biol Pharm Bull. 2015;38 (1) :30-8.