MPO-IN-6
MPO-IN-6 (compound ADC) is an electrophile with good antioxidant and anti-inflammatory properties. MPO-IN-6 is a myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD) inhibitor with IC50s of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 is a potential cardiovascular preventive agent[1].
Product Specifications
UNSPSC
12352005
Target
Dipeptidyl Peptidase; Glutathione Peroxidase; Glycosidase
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mpo-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C([N+]([O-])=O)C=C(OCO2)C2=C1)NC3=CC=CC(C(C)=O)=C3
Molecular Formula
C16H12N2O6
Molecular Weight
328.28
References & Citations
[1]Reshma Rajan, et al. Synthesis, Structural Elucidation, In Silico and In Vitro Studies of New Class of Methylenedioxyphenyl-Based Amide Derivatives as Potential Myeloperoxidase Inhibitors for Cardiovascular Protection. ACS Omega. 2024 Feb 7;9 (7) :7850-7868.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DPP-4
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TP313024L 1 mg
C20orf30 (TMEM230) (NM_001009924) Human Recombinant Protein
Sign In for Pricing
View Details 
AP50534PU-N 400 µL
C1orf144 (SZRD1) (N-term) Rabbit Polyclonal Antibody
Sign In for Pricing
View Details 
TP317977 20 µg
BAF53A (ACTL6A) (NM_004301) Human Recombinant Protein
Sign In for Pricing
View Details 
BNUM1317-50 1x 50 µL
Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL
Sign In for Pricing
View Details 
BNC042106-500 1x 500 µL
Replication Protein A2 (RPA2) (RPA2/2106), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details