Cathepsin D
Cathepsin D (CTSD) is a lysosomal aspartic protease encoded by the CTSD gene. Cathepsin D regulates lysosomal protease activity. Loss of Cathepsin D leads to lysosomal dysfunction and the accumulation of various cellular proteins associated with neurodegenerative diseases. Cathepsin D is involved in breast cancer metastasis. Cathepsin D can be used in research on diseases such as breast cancer and stroke[1][2].
Product Specifications
CAS Number
[9025-26-7]
Product Name Alternative
CTSD
UNSPSC
12352204
Target
Biochemical Assay Reagents
Type
Enzyme
Related Pathways
Others
Field of Research
Cancer; Cardiovascular Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cathepsin-d.html
Solubility
10 mM in DMSO
Smiles
[CathepsinD]
References & Citations
[1]Hossain MI, et al. Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective. Autophagy. 2021 Jun;17 (6) :1330-1348.|[2]Rochefort H, et al. Cathepsin D: a protease involved in breast cancer metastasis. Cancer Metastasis Rev. 1990 Dec;9 (4) :321-31.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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