DGKζ-IN-6
DGKζ-IN-6 (compound 40) is an oral active DGKζ inhibitor with the IC50 of 45.5 nM. DGKζ-IN-6 inhibits the secretion of IL-2 and can be used for study of cancer and autoimmune diseases[1].
Product Specifications
CAS Number
[3058005-75-4]
UNSPSC
12352005
Target
DGK; Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dgkζ-in-6.html
Smiles
CC(N(C1=NC(N)=C(S1)C(C2=CC=C(C=C2)OC3CC3)=O)C4=CC=C(C=C4)F)C(N)=O
Molecular Formula
C22H21FN4O3S
Molecular Weight
440.49
References & Citations
[1]Xie Yuli, et al. Thiazole compounds as DGKζ inhibitors. China, WO2024208198A1. 2024-10-10
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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