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DGKζ-IN-6

Product Specifications

UNSPSC Description

DGKζ-IN-6 (compound 40) is an oral active DGKζ inhibitor with the IC50 of 45.5 nM. DGKζ-IN-6 inhibits the secretion of IL-2 and can be used for study of cancer and autoimmune diseases[1].

Target Antigen

DGK; Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation;Metabolic Enzyme/Protease

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dgkζ-in-6.html

Smiles

CC(N(C1=NC(N)=C(S1)C(C2=CC=C(C=C2)OC3CC3)=O)C4=CC=C(C=C4)F)C(N)=O

Molecular Weight

440.49

References & Citations

[1]Xie Yuli, et al. Thiazole compounds as DGKζ inhibitors. China, WO2024208198A1. 2024-10-10

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-169317/DGKζ-IN-6-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-169317/

Clinical Information

No Development Reported

CAS Number

3058005-75-4

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