Human CBR4 Protein

<strong>Human CBR4 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011703_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 0.5 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> CBR-4 protein, CBR4, Quinone reductase CBR4 protein, CBR 4 protein, CBR-4, 3-oxoacyl-[acyl-carrier-protein] reductase, Carbonyl reductase family member 4 protein, CBR 4_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Santangelo A, Rossato M, Lombardi G, Benfatto S, Lavezzari D, De Salvo GL, Indraccolo S, Dechecchi MC, Prandini P, Gambari R, Scapoli C, Di Gennaro G, Caccese M, Eoli M, Rudà R, Brandes AA, Ibrahim T, Rizzato S, Lolli I, Lippi G, Delledonne M, Zagonel V, Cabrini G. A molecular signature associated with prolonged survival in glioblastoma patients treated with regorafenib Neuro Oncol. 2021 Feb 25;23(2):264-276._x000D_ 2: Malátková P, Maser E, Wsól V. Human carbonyl reductases Curr Drug Metab. 2010 Oct;11(8):639-58._x000D_ 3: Endo S, Matsunaga T, Kitade Y, Ohno S, Tajima K, El-Kabbani O, Hara A. Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase Biochem Biophys Res Commun. 2008 Dec 26;377(4):1326-30._x000D_ 4: Xu K, Bai Y, Zhang A, Zhang Q, Bartlam MG. Insights into the structure and architecture of the CCR4-NOT complex Front Genet. 2014 May 16;5:137._x000D_ 5: Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z. Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase Nat Commun. 2014 Sep 9;5:4805._x000D_ 6: Amai K, Fukami T, Ichida H, Watanabe A, Nakano M, Watanabe K, Nakajima M. Quantitative analysis of mRNA expression levels of aldo-keto reductase and short-chain dehydrogenase/reductase isoforms in human livers Drug Metab Pharmacokinet. 2020 Dec;35(6):539-547._x000D_ 7: Piccioni A, Gaetani E, Neri V, Gatto I, Palladino M, Silver M, Smith RC, Giarretta I, Pola E, Hlatky L, Pola R. Sonic hedgehog therapy in a mouse model of age-associated impairment of skeletal muscle regeneration J Gerontol A Biol Sci Med Sci. 2014 Mar;69(3):245-52._x000D_ 8: Bains OS, Grigliatti TA, Reid RE, Riggs KW. Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin J Pharmacol Exp Ther. 2010 Dec;335(3):533-45._x000D_ 9: Chen Z, Kastaniotis AJ, Miinalainen IJ, Rajaram V, Wierenga RK, Hiltunen JK. 17beta-hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS FASEB J. 2009 Nov;23(11):3682-91._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20723428">10: Zhou XY, Sun JF, He YH, Zhang HY, Yu J, Guo SC, Cai Y, Hu XC, Zhu JD. [Correlation of the methylation status of CpG islands in the promoter region of 10 genes with the 5-Fu chemosensitivity in 3 breast cancer cell lines] Zhonghua Zhong Liu Za Zhi. 2010 May;32(5):328-33.</a>_x000D_ _x000D_ <strong>Products Related to Human CBR4 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>