ONO 1301
ONO 1301 (ONO-AP 500-02), a prostaglandin (PG) I2 mimetic, is an orally active, long-acting prostacyclin agonist with thromboxane-synthase inhibitory activity. ONO 1301 promotes production of hepatocyte growth factor (HGF) from various cell types and ameliorates ischemia-induced left ventricle dysfunction in the mouse, rat and pig[1][2][3].
Product Specifications
CAS Number
176391-41-6
Product Name Alternative
ONO-AP 500-02
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ono-1301.html
Purity
99.02
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC(COC1=C2C(C(CCO/N=C(C3=CN=CC=C3)\C4=CC=CC=C4)=CCC2)=CC=C1)=O
Molecular Formula
C26H24N2O4
Molecular Weight
428.49
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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