(E/Z) -PG-11047
(E/Z) -PG-11047 ((E/Z) -CGC-11047) is a polyamine analog with potential application in lung cancer inhibition. (E/Z) -PG-11047 effectively inhibited the growth of non-small cell and small cell lung cancer cells. (E/Z) -PG-11047 exhibits significant biochemical effects in non-small cell lung cancer cells, resulting in significant downregulation of polyamine synthetase activity. (E/Z) -PG-11047 induces polyamine metabolism, resulting in a significant reduction in polyamine levels[1].
Product Specifications
CAS Number
949933-50-0
Product Name Alternative
(E/Z) -CGC-11047
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-z-pg-11047.html
Smiles
CCNCCCNC/C=C/CNCCCNCC
Molecular Formula
C14H32N4
Molecular Weight
256.43
References & Citations
[1]In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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