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(E/Z) -PG-11047

(E/Z) -PG-11047 ((E/Z) -CGC-11047) is a polyamine analog with potential application in lung cancer inhibition. (E/Z) -PG-11047 effectively inhibited the growth of non-small cell and small cell lung cancer cells. (E/Z) -PG-11047 exhibits significant biochemical effects in non-small cell lung cancer cells, resulting in significant downregulation of polyamine synthetase activity. (E/Z) -PG-11047 induces polyamine metabolism, resulting in a significant reduction in polyamine levels[1].

Product Specifications

CAS Number

949933-50-0

Product Name Alternative

(E/Z) -CGC-11047

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e-z-pg-11047.html

Smiles

CCNCCCNC/C=C/CNCCCNCC

Molecular Formula

C14H32N4

Molecular Weight

256.43

References & Citations

[1]In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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