Sulfiram
Sulfiram, an ectoparasiticide, is a weak aldehyde dehydrogenase (ALDH) inhibitor. Sulfiram can be used for the study of scabies[1][2].
Product Specifications
CAS Number
95-05-6
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Aldehyde Dehydrogenase (ALDH) ; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sulfiram.html
Purity
96.35
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
S=C(N(CC)CC)SC(N(CC)CC)=S
Molecular Formula
C10H20N2S3
Molecular Weight
264.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Mays DC, et al. Photolysis of sulfiram: a mechanism for its disulfiram-like reaction. Biochem Pharmacol. 1994 Nov 16;48 (10) :1917-25.|[2]Clare A Peters Libeu, et al. Altering APP proteolysis: increasing sAPPalpha production by targeting dimerization of the APP ectodomain. PLoS One. 2012;7 (6) :e40027.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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