Sulfiram

Sulfiram, an ectoparasiticide, is a weak aldehyde dehydrogenase (ALDH) inhibitor. Sulfiram can be used for the study of scabies[1][2].

Product Specifications

CAS Number

[95-05-6]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Aldehyde Dehydrogenase (ALDH) ; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sulfiram.html

Purity

96.35

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

S=C(N(CC)CC)SC(N(CC)CC)=S

Molecular Formula

C10H20N2S3

Molecular Weight

264.47

Precautions

H302, H315, H319, H335

References & Citations

[1]Mays DC, et al. Photolysis of sulfiram: a mechanism for its disulfiram-like reaction. Biochem Pharmacol. 1994 Nov 16;48 (10) :1917-25.|[2]Clare A Peters Libeu, et al. Altering APP proteolysis: increasing sAPPalpha production by targeting dimerization of the APP ectodomain. PLoS One. 2012;7 (6) :e40027.